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Dostinex 0.25mg 0.5mg 1mg – “Cabergoline, Cabaser, Prolastat, Cabotrim” “Parkinson’s Disease, Prolactinoma, Hyperprolactinemia”
Cabergoline (brand names Dostinex and others), an ergot derivative, is a potent dopamine receptor agonist on D 2 receptors. Rat studies show cabergoline has a direct inhibitory effect on pituitary lactotroph ( prolactin ) cells. It is frequently used as a first-line agent in the management of prolactinomas due to its higher affinity for D 2 receptor sites, less severe side effects, and more convenient dosing schedule than the older bromocriptine, though in pregnancy bromocripine is often still chosen since there is less data on safety in pregnancy for cabergoline.
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